Intrapleural fibrinolytic therapy by urokinase for acute empyema
نویسندگان
چکیده
منابع مشابه
Dose dependency of outcomes of intrapleural fibrinolytic therapy in new rabbit empyema models.
The incidence of empyema (EMP) is increasing worldwide; EMP generally occurs with pleural loculation and impaired drainage is often treated with intrapleural fibrinolytic therapy (IPFT) or surgery. A number of IPFT options are used clinically with empiric dosing and variable outcomes in adults. To evaluate mechanisms governing intrapleural fibrinolysis and disease outcomes, models of Pasteurell...
متن کاملFibrinolytic therapy for parapneumonic empyema during pregnancy
Pneumonia and parapneumonic complicated effusion during pregnancy is uncommon but poses potentially serious risks to both mother and fetus. Enzymatic debridement of the pleural cavity with fibrinolytic agents is a noninvasive option that can facilitate drainage and prevent the need for surgery. Herein, we describe the cases of two pregnant women with parapneumonic empyema who were successfully ...
متن کاملIntrapleural Fibrinolytic Therapy in Loculated Effusions
Loculated pleural effusions are most commonly due to complicated parapneumonic effusions and empyema followed by tubercular pleural effusions and empyema, hemothorax and malignant effusions. Loculations develop due to delayed initiation and inappropriate use of antibiotics and, delayed initiation of pleural space drainage. The presence of loculations and thick viscous fluid leads to failed pleu...
متن کاملComparison of Video-Assisted Thoracoscopic Surgery and Intrapleural Urokinase as an Initial Treatment for Parapneumonic Effusion and Thoracic Empyema
Introduction: The treatment of complicated parapneumonic effusion (PPE) and thoracic empyema (TE) is controversial; and the choice of treatment after confirming the failure of simple drainage remains unclear. The purpose of this study was to compare the outcomes of intrapleural urokinase (UK) administration and video-assisted thoracoscopic surgery (VATS) as initial treatment options for PPE and...
متن کاملIntrapleural fibrinolytic agents for empyema and complicated parapneumonic effusions: a meta-analysis.
BACKGROUND Randomized controlled trials have shown conflicting findings about the role of intrapleural fibrinolytic therapy for the treatment of empyema and complicated parapneumonic effusions in adult patients. OBJECTIVES To assess the clinical efficacy and summarize the current evidence of intrapleural fibrinolytic use in patients with empyema and complicated parapneumonic effusions in adul...
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ژورنال
عنوان ژورنال: The Journal of the Japanese Association for Chest Surgery
سال: 2020
ISSN: 0919-0945,1881-4158
DOI: 10.2995/jacsurg.34.301